The multi-center study enrolled 31,989 participants from 126 research centers in the US and Canada during the 2011–2012 and 2012–2013 influenza seasons in the Northern Hemisphere compared to the high-dose tricent vaccine. To be compared. Adults over 65 years of age.
“The study was conducted to see if using a high-dose vaccine was better than the normal vaccine compared to older adults. We were not aware of this therapeutic form until this trial took place. Better or not and now we know it is better., “Lead author Keep Talbot, MD, assistant professor of medicine, who coordinator for more than 100 study sites Served as Vesk.
“Older adults are the most susceptible to influenza; they get sick the most and are hospitalized the most. This vaccine works better than the standard dose and that’s why I want my patients to get a higher dose every year Say. In the meantime, we will continue to work to introduce new and improved vaccines for older adults. ”
Researchers concluded that the high-dose vaccine is safe, induces significantly higher antibody responses, and provides better protection from laboratory-confirmed influenza disease in individuals over 65 years of age than the standard dose.
Study data also indicated that high-dose vaccines may provide clinical benefits for the prevention of hospitalization, pneumonia, cardio-respiratory conditions, non-routine medical visits, and drug use.
Between 1990 and 1999, seasonal influenza caused an average of 36,000 deaths and 226,000 hospitalizations per year. Adults over the age of 65 are particularly vulnerable to complications of influenza, with most being responsible for seasonal influenza-related hospitals and deaths.
“Hospitalization for influenza prevention should reduce deaths, heart attacks, and pneumonia,” Talbot said. “This vaccine has somewhat more arm soreness than a normal vaccine because it is a higher dose. With this increase, the soreness gets more protection.”
Fluzone is known as the high-dose vaccine and made by Sanofi Pasteur, the inactivated influenza vaccine has four times the amount of antigen that is contained in the standard-dose fluorine vaccine.
David P., vice president of scientific and medical affairs. “Fluoxon high-dose vaccine is the only influenza vaccine in the US specifically designed to reverse the age-related deterioration of the immune system in older adults,” Greenberg said. And Chief Medical Officer, Sanofi Pasteur U.S.
The study authors stated that one-to-four success cases of influenza could be prevented if high-dose vaccines were used instead of standard-dose vaccines.
“I think that every year older adults are hospitalized with influenza and many of them come to the hospital with pneumonia and heart failure,” Talbot said, “but I have to say that our seniors in Nashville Vaccination are very good.
They are very good and they do much better than their counterparts who are under 65 years old. About 76 percent of older adults at this age are vaccinated with influenza every year. “